Journal of the Bahrain Medical Society
Year 2021, Volume 33, Issue 2, Pages 33-36
https://doi.org/10.26715/jbms.33_2021_2_6Haya AlBuainain1, Manal Abduljalil2, Nawal Dayoub3, Nayla Bushaqer4
1Resident, Department of Obstetrics and Gynecology, Bahrain Defence Force Royal Medical Services, Bahrain.
2Consultant Hematologist, Department of Internal Medicine, Bahrain Defence Force Royal Medical Services, Bahrain.
3Consultant Obstetrics, Gynecology and IVF Consultant, Assisted Reproduction and Gynecology Center, England, United Kingdom.
4Consultant Obstetrics, Gynecology and IVF Consultant, Department of Obstetrics and Gynecology, Bahrain Defence Force Royal Medical Services, Bahrain.
*Corresponding author: Haya AlBuainain, Contact Number: 00973 36900062, Email: haya.albuainain.11@gmail.com
Received date: November 24, 2020; Accepted date: April 28, 2021; Published date: June 30, 2021
Abstract
Beta-thalassemia is caused by a genetically mediated deletion of beta-globin chain of hemoglobin. It is an autosomal recessive disease, which causes a severe medical condition that requires longterm blood transfusions. An impaired hypothalamic-pituitary-ovarian axis mainly causes infertility in such patients. This case report presents a 26-year-old female, a known case of beta-thalassemia major, that received monthly blood transfusions before conceiving. The patient sought consultation for the treatment of primary infertility at Bahrain Defence Force Royal Medical Services (BDF-RMS) Hospital. The patient underwent two trials of intrauterine insemination (IUI). The goal was to build up endometrial thickness by gonadotrophins administration for embryo implantation. To conclude, IUI combined with gonadotrophins for ovarian stimulation has shown success.
Keywords: Artificial Insemination, Beta-Thalassemia, Hypogonadism, Infertility, Pregnancy