Journal of the Bahrain Medical Society

Year 2021, Volume 33, Issue 2, Pages 42-45

https://doi.org/10.26715/jbms.33_2020_2_8

Case Report

Hailey-Hailey Disease Treated Successfully with Acitretin

Fatema Abdulwahab Khamdan1, Maryam Ahmed Khamdan2

Author Affiliation

1Chief Dermatology Resident, MD, Salmaniya Medical Complex, Department of Dermatology, P.O. Box 12, Kingdom of Bahrain.

2General Practitioner, MD, Kingdom of Bahrain.

*Corresponding author: Dr. Fatema Khamdan, MD, Chief Dermatology Resident at Salmaniya Medical Complex, Department of Dermatology, P.O. Box 12, Kingdom of Bahrain, Email: fatimakhamdan@gmail.com, Dr.fatima.khamdan@gmail.com 

Received date: December 17, 2020; Accepted date: May 23, 2021; Published date: June 30, 2021


Abstract

Hailey-Hailey disease (HHD) is a rare genodermatosis characterized by acantholysis and dyskeratosis of the intertriginous areas. This article presents the case of a 41-year-old Bahraini male, not known to have any medical illness, who presented with a two-year history of bilateral, painful, fissured skin lesions on the groin and axilla. The diagnosis of HHD was confirmed by biopsy. The patient was treated with a course of acitretin 25mg once daily orally for three months, and the treatment led to significant improvement. Up to date, this is the first case to be reported in Bahrain. The case report demonstrated the benefit of using acitretin in the management of HHD.

Keywords: Acantholysis, Acitretin, Axilla, Benign Familial Pemphigus, Groin, Skin Disease

*Kindly refer to PDF for tables/images for this article